The convergence of Artificial Intelligence (AI) and blockchain technology is reshaping the digital world, offering decentralized, secure, and efficient AI services on blockchain platforms. Despite the promise, the high computational demands of AI on blockchain raise significant privacy and efficiency concerns. The Optimistic Privacy-Preserving AI (opp/ai) framework is introduced as a pioneering solution to these issues, striking a balance between privacy protection and computational efficiency. The framework integrates Zero-Knowledge Machine Learning (zkML) for privacy with Optimistic Machine Learning (opML) for efficiency, creating a hybrid model tailored for blockchain AI services. This study presents the opp/ai framework, delves into the privacy features of zkML, and assesses the framework's performance and adaptability across different scenarios.