Beyond 5G networks provide solutions for next-generation communications, especially digital twins networks (DTNs) have gained increasing popularity for bridging physical space and digital space. However, current DTNs networking frameworks pose a number of challenges especially when applied in scenarios that require high communication efficiency and multimodal data processing. First, current DTNs frameworks are unavoidable regarding high resource consumption and communication congestion because of original bit-level communication and high-frequency computation, especially distributed learning-based DTNs. Second, current machine learning models for DTNs are domain-specific (e.g. E-health), making it difficult to handle DT scenarios with multimodal data processing requirements. Last but not least, current security schemes for DTNs, such as blockchain, introduce additional overheads that impair the efficiency of DTNs. To address the above challenges, we propose a large language model (LLM) empowered DTNs networking framework, LLM-Twin. First, we design the mini-giant model collaboration scheme to achieve efficient deployment of LLM in DTNs, since LLM are naturally conducive to processing multimodal data. Then, we design a semantic-level high-efficiency, and secure communication model for DTNs. The feasibility of LLM-Twin is demonstrated by numerical experiments and case studies. To our knowledge, this is the first to propose LLM-based semantic-level digital twin networking framework.