This paper focuses on the construction of non-intrusive Scientific Machine Learning (SciML) Reduced-Order Models (ROMs) for nonlinear, chaotic plasma turbulence simulations. In particular, we propose using Operator Inference (OpInf) to build low-cost physics-based ROMs from data for such simulations. As a representative example, we focus on the Hasegawa-Wakatani (HW) equations used for modeling two-dimensional electrostatic drift-wave plasma turbulence. For a comprehensive perspective of the potential of OpInf to construct accurate ROMs for this model, we consider a setup for the HW equations that leads to the formation of complex, nonlinear, and self-driven dynamics, and perform two sets of experiments. We first use the data obtained via a direct numerical simulation of the HW equations starting from a specific initial condition and train OpInf ROMs for predictions beyond the training time horizon. In the second, more challenging set of experiments, we train ROMs using the same dataset as before but this time perform predictions for six other initial conditions. Our results show that the OpInf ROMs capture the important features of the turbulent dynamics and generalize to new and unseen initial conditions while reducing the evaluation time of the high-fidelity model by up to five orders of magnitude in single-core performance. In the broader context of fusion research, this shows that non-intrusive SciML ROMs have the potential to drastically accelerate numerical studies, which can ultimately enable tasks such as the design and real-time control of optimized fusion devices.