FlexRDZ is an online, autonomous manager for radio dynamic zones (RDZ) that seeks to enable the safe operation of RDZs through real-time control of deployed test transmitters. FlexRDZ leverages Hierarchical Task Networks and digital twin modeling to plan and resolve RDZ violations in near real-time. We prototype FlexRDZ with GTPyhop and the Terrain Integrated Rough Earth Model (TIREM). We deploy and evaluate FlexRDZ within a simulated version of the Salt Lake City POWDER testbed, a potential urban RDZ environment. Our simulations show that FlexRDZ enables up to a 20 dBm reduction in mobile interference and a significant reduction in the total power of leaked transmissions while preserving the overall communication capabilities and uptime of test transmitters. To our knowledge, FlexRDZ is the first autonomous system for RDZ management.