We present ideas about creating a next generation Intrusion Detection System based on the latest immunological theories. The central challenge with computer security is determining the difference between normal and potentially harmful activity. For half a century, developers have protected their systems by coding rules that identify and block specific events. However, the nature of current and future threats in conjunction with ever larger IT systems urgently requires the development of automated and adaptive defensive tools. A promising solution is emerging in the form of Artificial Immune Systems. The Human Immune System can detect and defend against harmful and previously unseen invaders, so can we not build a similar Intrusion Detection System for our computers.