Many industrial and real life problems exhibit highly nonlinear periodic behaviors and the conventional methods may fall short of finding their analytical or closed form solutions. Such problems demand some cutting edge computational tools with increased functionality and reduced cost. Recently, deep neural networks have gained massive research interest due to their ability to handle large data and universality to learn complex functions. In this work, we put forward a methodology based on deep neural networks with responsive layers structure to deal nonlinear oscillations in microelectromechanical systems. We incorporated some oscillatory and non oscillatory activation functions such as growing cosine unit known as GCU, Sine, Mish and Tanh in our designed network to have a comprehensive analysis on their performance for highly nonlinear and vibrational problems. Integrating oscillatory activation functions with deep neural networks definitely outperform in predicting the periodic patterns of underlying systems. To support oscillatory actuation for nonlinear systems, we have proposed a novel oscillatory activation function called Amplifying Sine Unit denoted as ASU which is more efficient than GCU for complex vibratory systems such as microelectromechanical systems. Experimental results show that the designed network with our proposed activation function ASU is more reliable and robust to handle the challenges posed by nonlinearity and oscillations. To validate the proposed methodology, outputs of our networks are being compared with the results from Livermore solver for ordinary differential equation called LSODA. Further, graphical illustrations of incurred errors are also being presented in the work.