Recently developed large language models have achieved remarkable success in generating fluent and coherent text. However, these models often tend to 'hallucinate' which critically hampers their reliability. In this work, we address this crucial problem and propose an approach that actively detects and mitigates hallucinations during the generation process. Specifically, we first identify the candidates of potential hallucination leveraging the model's logit output values, check their correctness through a validation procedure, mitigate the detected hallucinations, and then continue with the generation process. Through extensive experiments with the 'article generation task', we first demonstrate the individual efficacy of our detection and mitigation techniques. Specifically, the detection technique achieves a recall of 88% and the mitigation technique successfully mitigates 57.6% of the correctly detected hallucinations. Importantly, our mitigation technique does not introduce new hallucinations even in the case of incorrectly detected hallucinations, i.e., false positives. Then, we show that the proposed active detection and mitigation approach successfully reduces the hallucinations of the GPT-3 model from 47.5% to 14.5% on average. In summary, our work contributes to improving the reliability and trustworthiness of large language models, a crucial step en route to enabling their widespread adoption in real-world applications.