Semantic communications have emerged as a promising solution to address the challenge of efficient communication in rapidly evolving and increasingly complex Internet of Things (IoT) networks. However, protecting the security of semantic communication systems within the distributed and heterogeneous IoT networks is critical issues that need to be addressed. We develop a secure and efficient distributed semantic communication system in IoT scenarios, focusing on three aspects: secure system maintenance, efficient system update, and privacy-preserving system usage. Firstly, we propose a blockchain-based interaction framework that ensures the integrity, authentication, and availability of interactions among IoT devices to securely maintain system. This framework includes a novel digital signature verification mechanism designed for semantic communications, enabling secure and efficient interactions with semantic communications. Secondly, to improve the efficiency of interactions, we develop a flexible semantic communication scheme that leverages compressed semantic knowledge bases. This scheme reduces the data exchange required for system update and is adapt to dynamic task requirements and the diversity of device capabilities. Thirdly, we exploit the integration of differential privacy into semantic communications. We analyze the implementation of differential privacy taking into account the lossy nature of semantic communications and wireless channel distortions. An joint model-channel noise mechanism is introduced to achieve differential privacy preservation in semantic communications without compromising the system's functionality. Experiments show that the system is able to achieve integrity, availability, efficiency and the preservation of privacy.