Neural networks play an important role in crop-weed classification have high accuracy more than 95%. Manually choosing models and fine-tuning are laborious, yet it is indispensable in most traditional practices and researches. Moreover, classic training metric are not thoroughly compatible with farming tasks, that a model still have a noticeable chance of miss classifying crop to weed while it reach higher accuracy even more than 99%. In this paper we demonstrate a methodology of weed-crop classification based on autonomous models choosing and ensemble that could make models choosing and tunning automatically, and improve the prediction with high accuracy(>99% for both data set) in specific class with low risk in incorrect predicting.