In this paper we argue that a jailbroken GenAI model can cause substantial harm to GenAI-powered applications and facilitate PromptWare, a new type of attack that flips the GenAI model's behavior from serving an application to attacking it. PromptWare exploits user inputs to jailbreak a GenAI model to force/perform malicious activity within the context of a GenAI-powered application. First, we introduce a naive implementation of PromptWare that behaves as malware that targets Plan & Execute architectures (a.k.a., ReAct, function calling). We show that attackers could force a desired execution flow by creating a user input that produces desired outputs given that the logic of the GenAI-powered application is known to attackers. We demonstrate the application of a DoS attack that triggers the execution of a GenAI-powered assistant to enter an infinite loop that wastes money and computational resources on redundant API calls to a GenAI engine, preventing the application from providing service to a user. Next, we introduce a more sophisticated implementation of PromptWare that we name Advanced PromptWare Threat (APwT) that targets GenAI-powered applications whose logic is unknown to attackers. We show that attackers could create user input that exploits the GenAI engine's advanced AI capabilities to launch a kill chain in inference time consisting of six steps intended to escalate privileges, analyze the application's context, identify valuable assets, reason possible malicious activities, decide on one of them, and execute it. We demonstrate the application of APwT against a GenAI-powered e-commerce chatbot and show that it can trigger the modification of SQL tables, potentially leading to unauthorized discounts on the items sold to the user.