Abstract:Panoramic radiography (panoramic X-ray, PX) is a widely used imaging modality for dental examination. However, its applicability is limited as compared to 3D Cone-beam computed tomography (CBCT), because PX only provides 2D flattened images of the oral structure. In this paper, we propose a new framework which estimates 3D oral structure from real-world PX images. Since there are not many matching PX and CBCT data, we used simulated PX from CBCT for training, however, we used real-world panoramic radiographs at the inference time. We propose a new ray-sampling method to make simulated panoramic radiographs inspired by the principle of panoramic radiography along with the rendering function derived from the Beer-Lambert law. Our model consists of three parts: translation module, generation module, and refinement module. The translation module changes the real-world panoramic radiograph to the simulated training image style. The generation module makes the 3D structure from the input image without any prior information such as a dental arch. Our ray-based generation approach makes it possible to reverse the process of generating PX from oral structure in order to reconstruct CBCT data. Lastly, the refinement module enhances the quality of the 3D output. Results show that our approach works better for simulated and real-world images compared to other state-of-the-art methods.