Abstract:Using medical imaging as case-study, we demonstrate how Intel-optimized TensorFlow on an x86-based server equipped with 2nd Generation Intel Xeon Scalable Processors with large system memory allows for the training of memory-intensive AI/deep-learning models in a scale-up server configuration. We believe our work represents the first training of a deep neural network having large memory footprint (~ 1 TB) on a single-node server. We recommend this configuration to scientists and researchers who wish to develop large, state-of-the-art AI models but are currently limited by memory.