A comprehensive study on Blood Cancer detection and classification using Convolutional Neural Network

Over the years in object detection several efficient Convolutional Neural Networks (CNN) networks, such as DenseNet201, InceptionV3, ResNet152v2, SEresNet152, VGG19, Xception gained significant attention due to their performance. Moreover, CNN paradigms have expanded to transfer learning and ensemble models from original CNN architectures. Research studies suggest that transfer learning and ensemble models are capable of increasing the accuracy of deep learning (DL) models. However, very few studies have conducted comprehensive experiments utilizing these techniques in detecting and localizing blood malignancies. Realizing the gap, this study conducted three experiments; in the first experiment -- six original CNNs were used, in the second experiment -- transfer learning and, in the third experiment a novel ensemble model DIX (DenseNet201, InceptionV3, and Xception) was developed to detect and classify blood cancer. The statistical result suggests that DIX outperformed the original and transfer learning performance, providing an accuracy of 99.12%. However, this study also provides a negative result in the case of transfer learning, as the transfer learning did not increase the accuracy of the original CNNs. Like many other cancers, blood cancer diseases require timely identification for effective treatment plans and increased survival possibilities. The high accuracy in detecting and categorization blood cancer detection using CNN suggests that the CNN model is promising in blood cancer disease detection. This research is significant in the fields of biomedical engineering, computer-aided disease diagnosis, and ML-based disease detection.