Abstract:The biggest challenge in the application of deep learning to the medical domain is the availability of training data. Data augmentation is a typical methodology used in machine learning when confronted with a limited data set. In a classical approach image transformations i.e. rotations, cropping and brightness changes are used. In this work, a StyleGAN2-ADA model of Generative Adversarial Networks is trained on the limited COVID-19 chest X-ray image set. After assessing the quality of generated images they are used to increase the training data set improving its balance between classes. We consider the multi-class classification problem of chest X-ray images including the COVID-19 positive class that hasn't been yet thoroughly explored in the literature. Results of transfer learning-based classification of COVID-19 chest X-ray images are presented. The performance of several deep convolutional neural network models is compared. The impact on the detection performance of classical image augmentations i.e. rotations, cropping, and brightness changes are studied. Furthermore, classical image augmentation is compared with GAN-based augmentation. The most accurate model is an EfficientNet-B0 with an accuracy of 90.2 percent, trained on a dataset with a simple class balancing. The GAN augmentation approach is found to be subpar to classical methods for the considered dataset.