Cognitive Assessment Estimation from Behavioral Responses in Emotional Faces Evaluation Task -- AI Regression Approach for Dementia Onset Prediction in Aging Societies

We present a practical health-theme machine learning (ML) application concerning `AI for social good' domain for `Producing Good Outcomes' track. In particular, the solution is concerning the problem of a potential elderly adult dementia onset prediction in aging societies. The paper discusses our attempt and encouraging preliminary study results of behavioral responses analysis in a working memory-based emotional evaluation experiment. We focus on the development of digital biomarkers for dementia progress detection and monitoring. We present a behavioral data collection concept for a subsequent AI-based application together with a range of regression encouraging results of Montreal Cognitive Assessment (MoCA) scores in the leave-one-subject-out cross-validation setup. The regressor input variables include experimental subject's emotional valence and arousal recognition responses, as well as reaction times, together with self-reported education levels and ages, obtained from a group of twenty older adults taking part in the reported data collection project. The presented results showcase the potential social benefits of artificial intelligence application for elderly and establish a step forward to develop ML approaches, for the subsequent application of simple behavioral objective testing for dementia onset diagnostics replacing subjective MoCA.

Brain correlates of task-load and dementia elucidation with tensor machine learning using oddball BCI paradigm

Dementia in the elderly has recently become the most usual cause of cognitive decline. The proliferation of dementia cases in aging societies creates a remarkable economic as well as medical problems in many communities worldwide. A recently published report by The World Health Organization (WHO) estimates that about 47 million people are suffering from dementia-related neurocognitive declines worldwide. The number of dementia cases is predicted by 2050 to triple, which requires the creation of an AI-based technology application to support interventions with early screening for subsequent mental wellbeing checking as well as preservation with digital-pharma (the so-called beyond a pill) therapeutical approaches. We present an attempt and exploratory results of brain signal (EEG) classification to establish digital biomarkers for dementia stage elucidation. We discuss a comparison of various machine learning approaches for automatic event-related potentials (ERPs) classification of a high and low task-load sound stimulus recognition. These ERPs are similar to those in dementia. The proposed winning method using tensor-based machine learning in a deep fully connected neural network setting is a step forward to develop AI-based approaches for a subsequent application for subjective- and mild-cognitive impairment (SCI and MCI) diagnostics.