ZeroSlide: Is Zero-Shot Classification Adequate for Lifelong Learning in Whole-Slide Image Analysis in the Era of Pathology Vision-Language Foundation Models?

Lifelong learning for whole slide images (WSIs) poses the challenge of training a unified model to perform multiple WSI-related tasks, such as cancer subtyping and tumor classification, in a distributed, continual fashion. This is a practical and applicable problem in clinics and hospitals, as WSIs are large, require storage, processing, and transfer time. Training new models whenever new tasks are defined is time-consuming. Recent work has applied regularization- and rehearsal-based methods to this setting. However, the rise of vision-language foundation models that align diagnostic text with pathology images raises the question: are these models alone sufficient for lifelong WSI learning using zero-shot classification, or is further investigation into continual learning strategies needed to improve performance? To our knowledge, this is the first study to compare conventional continual-learning approaches with vision-language zero-shot classification for WSIs. Our source code and experimental results will be available soon.

Exploring the Limitations of Kolmogorov-Arnold Networks in Classification: Insights to Software Training and Hardware Implementation

Kolmogorov-Arnold Networks (KANs), a novel type of neural network, have recently gained popularity and attention due to the ability to substitute multi-layer perceptions (MLPs) in artificial intelligence (AI) with higher accuracy and interoperability. However, KAN assessment is still limited and cannot provide an in-depth analysis of a specific domain. Furthermore, no study has been conducted on the implementation of KANs in hardware design, which would directly demonstrate whether KANs are truly superior to MLPs in practical applications. As a result, in this paper, we focus on verifying KANs for classification issues, which are a common but significant topic in AI using four different types of datasets. Furthermore, the corresponding hardware implementation is considered using the Vitis high-level synthesis (HLS) tool. To the best of our knowledge, this is the first article to implement hardware for KAN. The results indicate that KANs cannot achieve more accuracy than MLPs in high complex datasets while utilizing substantially higher hardware resources. Therefore, MLP remains an effective approach for achieving accuracy and efficiency in software and hardware implementation.