Analysis of supervised and semi-supervised GrowCut applied to segmentation of masses in mammography images

Breast cancer is already one of the most common form of cancer worldwide. Mammography image analysis is still the most effective diagnostic method to promote the early detection of breast cancer. Accurately segmenting tumors in digital mammography images is important to improve diagnosis capabilities of health specialists and avoid misdiagnosis. In this work, we evaluate the feasibility of applying GrowCut to segment regions of tumor and we propose two GrowCut semi-supervised versions. All the analysis was performed by evaluating the application of segmentation techniques to a set of images obtained from the Mini-MIAS mammography image database. GrowCut segmentation was compared to Region Growing, Active Contours, Random Walks and Graph Cut techniques. Experiments showed that GrowCut, when compared to the other techniques, was able to acquire better results for the metrics analyzed. Moreover, the proposed semi-supervised versions of GrowCut was proved to have a clinically satisfactory quality of segmentation.

A semi-supervised fuzzy GrowCut algorithm to segment and classify regions of interest of mammographic images

According to the World Health Organization, breast cancer is the most common form of cancer in women. It is the second leading cause of death among women round the world, becoming the most fatal form of cancer. Mammographic image segmentation is a fundamental task to support image analysis and diagnosis, taking into account shape analysis of mammary lesions and their borders. However, mammogram segmentation is a very hard process, once it is highly dependent on the types of mammary tissues. In this work we present a new semi-supervised segmentation algorithm based on the modification of the GrowCut algorithm to perform automatic mammographic image segmentation once a region of interest is selected by a specialist. In our proposal, we used fuzzy Gaussian membership functions to modify the evolution rule of the original GrowCut algorithm, in order to estimate the uncertainty of a pixel being object or background. The main impact of the proposed method is the significant reduction of expert effort in the initialization of seed points of GrowCut to perform accurate segmentation, once it removes the need of selection of background seeds. We also constructed an automatic point selection process based on the simulated annealing optimization method, avoiding the need of human intervention. The proposed approach was qualitatively compared with other state-of-the-art segmentation techniques, considering the shape of segmented regions. In order to validate our proposal, we built an image classifier using a classical multilayer perceptron. We used Zernike moments to extract segmented image features. This analysis employed 685 mammograms from IRMA breast cancer database, using fat and fibroid tissues. Results show that the proposed technique could achieve a classification rate of 91.28\% for fat tissues, evidencing the feasibility of our approach.