Pixel binning enables high speed, low power readout in low resolution modes, and more importantly, a reduction of read noise via floating diffusion binning. New, high resolution CMOS image sensors for mobile phones have moved beyond the once-binnable Quad Bayer and RGBW-Kodak patterns to the twice binnable Hexadeca Bayer pattern featuring 4x4 tiles of like colored pixels.Pixel binning enables high speed, low power readout in low resolution modes, and more importantly, a reduction of read noise via floating diffusion binning. New, high resolution CMOS image sensors for mobile phones have moved beyond the once-binnable Quad Bayer and RGBW-Kodak patterns to the twice binnable Hexadeca Bayer pattern featuring 4x4 tiles of like colored pixels. In this paper we present the non-intuitive result that Nona and Hexadeca Bayer can be superior to Quad Bayer in demosaicking quality due to degeneracies in the latter's spectrum. Hexadeca Bayer, nevertheless, suffers from the weakness of generating Quad Bayer after one round of binning. We present a novel twice binnable RGBW CFA, composed of 2x2 tiles capable of 4:1 floating diffusion binning, that is free from spectral degeneracies and thus demosaick well in full resolution and both binned modes. It also has a 4 dB low light SNR advantage over Quad and Hexadeca Bayer in the full resolution mode, and 6 dB SNR advantage in both the binned modes.