Training Frozen Feature Pyramid DINOv2 for Eyelid Measurements with Infinite Encoding and Orthogonal Regularization

Accurate measurement of eyelid parameters such as Margin Reflex Distances (MRD1, MRD2) and Levator Function (LF) is critical in oculoplastic diagnostics but remains limited by manual, inconsistent methods. This study evaluates deep learning models: SE-ResNet, EfficientNet, and the vision transformer-based DINOv2 for automating these measurements using smartphone-acquired images. We assess performance across frozen and fine-tuned settings, using MSE, MAE, and R2 metrics. DINOv2, pretrained through self-supervised learning, demonstrates superior scalability and robustness, especially under frozen conditions ideal for mobile deployment. Lightweight regressors such as MLP and Deep Ensemble offer high precision with minimal computational overhead. To address class imbalance and improve generalization, we integrate focal loss, orthogonal regularization, and binary encoding strategies. Our results show that DINOv2 combined with these enhancements delivers consistent, accurate predictions across all tasks, making it a strong candidate for real-world, mobile-friendly clinical applications. This work highlights the potential of foundation models in advancing AI-powered ophthalmic care.