Change detection (CD) is a fundamental task in Earth observation. While most change detection methods detect all changes, there is a growing need for specialized methods targeting specific changes relevant to particular applications while discarding the other changes. For instance, urban management might prioritize detecting the disappearance of buildings due to natural disasters or other reasons. Furthermore, while most supervised change detection methods require large-scale training datasets, in many applications only one or two training examples might be available instead of large datasets. Addressing such needs, we propose a focused CD approach using the Segment Anything Model (SAM), a versatile vision foundation model. Our method leverages a binary mask of the object of interest in pre-change images to detect their disappearance in post-change images. By using SAM's robust segmentation capabilities, we create prompts from the pre-change mask, use those prompts to segment the post-change image, and identify missing objects. This unsupervised approach demonstrated for building disappearance detection, is adaptable to various domains requiring specialized CD. Our contributions include defining a novel CD problem, proposing a method using SAM, and demonstrating its effectiveness. The proposed method also has benefits related to privacy preservation.