Mechanisms for data recovery and packet reliability are essential components of the upcoming 6th generation (6G) communication system. In this paper, we evaluate the interaction between a fast hybrid automatic repeat request (HARQ) scheme, present in the physical and medium access control layers, and a higher layer automatic repeat request (ARQ) scheme which may be present in the radio link control layer. Through extensive system-level simulations, we show that despite its higher complexity, a fast HARQ scheme yields > 66 % downlink average user throughput gains over simpler solutions without energy combining gains and orders of magnitude larger gains for users in challenging radio conditions. We present results for the design trade-off between HARQ and higher-layer data recovery mechanisms in the presence of realistic control and data channel errors, network delays, and transport protocols. We derive that, with a suitable design of 6G control and data channels reaching residual errors at the medium access control layer of 5 E-5 or better, a higher layer data recovery mechanism can be disabled. We then derive design targets for 6G control channel design, as well as promising enhancements to 6G higher layer data recovery to extend support for latency-intolerant services.