The rapid growth of the travel industry has increased the need for real-time optimization in reservation systems that could take care of huge data and transaction volumes. This study proposes a hybrid framework that ut folds an Artificial Intelligence and a Microservices approach for the performance optimization of the system. The AI algorithms forecast demand patterns, optimize the allocation of resources, and enhance decision-making driven by Microservices architecture, hence decentralizing system components for scalability, fault tolerance, and reduced downtime. The model provided focuses on major problems associated with the travel reservation systems such as latency of systems, load balancing and data consistency. It endows the systems with predictive models based on AI improved ability to forecast user demands. Microservices would also take care of different scales during uneven traffic patterns. Hence, both aspects ensure better handling of peak loads and spikes while minimizing delays and ensuring high service quality. A comparison was made between traditional reservation models, which are monolithic and the new model of AI-Microservices. Comparatively, the analysis results state that there is a drastic improvement in processing times where the system uptime and resource utilization proved the capability of AI and the microservices in transforming the travel industry in terms of reservation. This research work focused on AI and Microservices towards real-time optimization, providing critical insight into how to move forward with practical recommendations for upgrading travel reservation systems with this technology.