Parkinson gait modelling from an anomaly deep representation

Parkinson's Disease is associated with gait movement disorders, such as postural instability, stiffness, and tremors. Today, some approaches implemented learning representations to quantify kinematic patterns during locomotion, supporting clinical procedures such as diagnosis and treatment planning. These approaches assumes a large amount of stratified and labeled data to optimize discriminative representations. Nonetheless, these considerations may restrict the operability of approaches in real scenarios during clinical practice. This work introduces a self-supervised generative representation, under the pretext of video reconstruction and anomaly detection framework. This architecture is trained following a one-class weakly supervised learning to avoid inter-class variance and approach the multiple relationships that represent locomotion. For validation 14 PD patients and 23 control subjects were recorded, and trained with the control population only, achieving an AUC of 86.9%, homoscedasticity level of 80% and shapeness level of 70% in the classification task considering its generalization.