The examination of Osteoarthritis disease through X-ray by rheumatology can be classified into four grade of severity. This paper discusses about the application of artificial neural network backpropagation method for measuring the severity of the disease, where the observed X-ray range from wrist to fingers. The main procedures of system in this paper is divided into three, which are image processing, feature extraction, and artificial neural network process. First, an X-ray image digital (200x150 pixels and greyscale) will be thresholded, then extracted features based on probabilistic values of the color intensity of seven bit quantization result, and statistical textures. That feature values then will be normalizing to interval [0.1, 0.9], and then the result would be processing on backpropagation artificial neural network system as input to determine the severity of disease from an X-ray had input before it. From testing with learning rate 0.3, momentum 0.4, hidden units five pieces and about 132 feature vectors, this system had had a level of accuracy of 100% for learning data, 80% for learning and non-learning data, and 66.6% for non-learning data