This paper systematically analyzes the typical application scenarios and key technical challenges of AI in 6G air interface transmission, covering important areas such as performance enhancement of single functional modules, joint optimization of multiple functional modules, and low-complexity solutions to complex mathematical problems. Innovatively, a three-dimensional joint optimization design criterion is proposed, which comprehensively considers AI capability, quality, and cost. By maximizing the ratio of multi-scenario communication capability to comprehensive cost, a triangular equilibrium is achieved, effectively addressing the lack of consideration for quality and cost dimensions in existing design criteria. The effectiveness of the proposed method is validated through multiple design examples, and the technical pathways and challenges for air interface AI standardization are thoroughly discussed. This provides significant references for the theoretical research and engineering practice of 6G air interface AI technology.