Bayesian regularization-backpropagation neural network (BR-BPNN), a machine learning algorithm, is employed to predict some aspects of the gecko spatula peeling such as the variation of the maximum normal and tangential pull-off forces and the resultant force angle at detachment with the peeling angle. The input data is taken from finite element (FE) peeling results. The neural network is trained with 75% of the FE dataset. The remaining 25% are utilized to predict the peeling behavior. The training performance is evaluated for every change in the number of hidden layer neurons to determine the optimal network structure. The relative error is calculated to draw a clear comparison between predicted and FE results. It is observed that BR-BPNN models have significant potential to estimate the peeling behavior.